Author

Paul A. Cobine

Auburn UniversityORCID 0000-0001-6012-0985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Alison JaccardiD· 1 shared Andrew F. Jarvis· 1 shared Caroline BartmaniD· 1 shared Donita C. BradyiD· 1 shared Dusanka MilenkoviciD· 1 shared Elodie Vimont· 1 shared Erminia DonnarummaiD· 1 shared Esthel PénardiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alison JaccardORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 22, 2026

Mitochondrial copper stabilizes lipoylated TCA cycle proteins to sustain metabolism and proliferation

Santanu Ghosh, Andrew F. Jarvis, Jordi C. J. Hintzen…·Donita C. Brady

This study shows mitochondrial copper stabilizes lipoylated TCA cycle proteins, maintaining metabolism and proliferation by supporting lipoylation and TCA cycle function.

1 citation

metabolomicsexperimental assay

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Cell BiologybioRxivPreprintAug 18, 2025

Mutant CHCHD10 disrupts cytochrome c oxidation and activates retrograde signaling in a model of cardiomyopathy.

Márcio A. C. Ribeiro, Erminia Donnarumma, Hendrik Nolte…·Timothy Wai

This study shows that mutant CHCHD10 causes mitochondrial dysfunction and cardiomyopathy by disrupting cytochrome c oxidation and activating retrograde signaling.

DOI 10.1101/2025.08.18.668848

mouseproteomics

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MicrobiologyFEBS JournalPeer-reviewedDec 5, 2024

Copper trafficking in Trypanosoma cruzi: the transcriptional response of candidates to balance toxicity and recruitment

Marcelo Luciano Merli, María G. Mediavilla, Xinyu Zhu…·Julia A. Cricco

This study investigates copper metabolism in Trypanosoma cruzi, identifying key genes and proposing a model for copper transport and distribution during different life stages.

4 citations

bulk RNA-seqexperimental assay

𝕏 PostBluesky