Author

Andrew F. Jarvis

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Donita C. BradyiD· 2 shared George M. BurslemiD· 2 shared Ahlenne L. Abreu· 1 shared Alison JaccardiD· 1 shared Caroline BartmaniD· 1 shared Gina M. DeNicolaiD· 1 shared Jordi C. J. HintzeniD· 1 shared Kaitlyn ToyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Donita C. BradyORCID

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Author profile →

2 papers

Recent·Most cited

Mitochondrial copper stabilizes lipoylated TCA cycle proteins to sustain metabolism and proliferation

Santanu Ghosh, Andrew F. Jarvis, Jordi C. J. Hintzen, Nate R. McKnight, Pedro Costa‐Pinheiro, Noelle H. Nouhgton, Yumi Kim, Alison Jaccard, Scot C. Leary, Paul A. Cobine, Caroline Bartman, Gina M. DeNicola, Nathaniel W. Snyder, Kathryn E. Wellen, George M. Burslem, Donita C. Brady

This study shows mitochondrial copper stabilizes lipoylated TCA cycle proteins, maintaining metabolism and proliferation by supporting lipoylation and TCA cycle function.

bioRxiv · May 22, 2026 · PreprintCell Biology

MAPK Pathway Inhibition Reshapes Kinase Chemical Probe Reactivity Reflecting Cellular Activation States

Andrew F. Jarvis, Mohd Younis Bhat, Timothé Maujean, Ahlenne L. Abreu, Kaitlyn Toy, George M. Burslem, Donita C. Brady

This study uses ABPP to show how MAPK pathway inhibitors alter kinase residue reactivity, reflecting conformational changes and resistance mechanisms in melanoma cells.

ACS Bio & Med Chem Au · Jan 23, 2026Peer-reviewedCancer Biology