Author
The Netherlands Cancer InstituteORCID 0000-0001-6032-2034Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Xabier Vergara, Anna G. Manjón, Marcel de Haas…·Bas van Steensel
A multiplexed screen reveals how dozens of proteins sense the local chromatin context to tune the balance between two DNA repair pathways.
Ruben Schep, Max Trauernicht, Xabier Vergara…·Bas van Steensel
This study identifies 67 epigenetic drugs that modulate CRISPR-Cas9 editing efficiency and repair outcomes based on chromatin context in human cells.
Ruben Schep, Eva Karina Brinkman, Christ Leemans…·Bas van Steensel
The paper measures how chromatin context influences the balance between DNA repair pathways after Cas9-induced breaks in over 1,000 genomic locations.