David L. Aylor

The paper investigates sex-specific molecular responses to early-life toxicant exposures in mice across multiple life stages using transcriptomic and epigenomic data.

The paper predicts gene-environment interactions for toxicant susceptibility across global populations using AHR gene variation and 1000 Genomes Project data.

The paper characterizes persistent epigenomic and transcriptomic changes in mice exposed to environmental toxicants across life stages, revealing widespread gene expression and chromatin alterations.

The paper shows early-life toxicant exposure reprograms epigenomic aging, altering gene expression in liver cells and disease risk in adulthood.

This study identifies a genetic locus that reduces infarct size after ischemic stroke in mice, independent of collateral vessel anatomy, by uncovering the neuroprotective role of Msr1.

This study shows that age and genetic background influence hybrid male sterility in house mice, revealing age-dependent fertility changes and multiple modifier alleles.

The paper identifies four new neuroprotective loci modulating cerebral infarct volume in mice by comparing wild-derived strains and finds candidate genes associated with these loci.