Author

Adele Xu

Stanford MedicineORCID 0000-0003-3332-5285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Maria BarnaiD· 2 shared Alicia SolórzanoiD· 1 shared Andrew M. WatkinsiD· 1 shared Bojan Tunguz· 1 shared Christian A. ChoeiD· 1 shared Craig H. KerriD· 1 shared Daphna RothschildiD· 1 shared Davide RuggeroiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetics

Maria BarnaORCID

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2 papers

Recent·Most cited

GeneticseLifePeer-reviewedJun 12, 2023

Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs in vertebrates

Adele Xu, Rut Molinuevo, Elisa Fazzari…·Maria Barna

The paper investigates the evolutionary retention of ribosomal protein paralogs eS27 and eS27L by showing their subfunctionalized expression patterns are necessary for maintaining total protein expression across cell types.

18 citations

mouseexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedMar 22, 2022

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang…·Rhiju Das

This study develops PERSIST-seq and In-line-seq to optimize mRNA stability and translation, finding that in-cell stability is more critical than ribosome load for protein output.

400 citationstop 1%

humanmultiome

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