Author

Yixuan Huang

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anan LiiD· 1 shared Bella Raykowski· 1 shared Ben Yi TewiD· 1 shared Bing LiiD· 1 shared Chak Foon TsoiD· 1 shared Chenyan MaiD· 1 shared Chi Woo YooniD· 1 shared Chi XiaoiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Anan LiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineering Upd-like to broadly restrict arbovirus infection and vector competence in mosquitoes

陶新军, Wenfeng He, Huijun Zhang, Yan Zhang, Jianan Hao, Yixuan Huang, Fangming Xiang, Lu Liu, Raghda Nasser, Erol Fikrig, Nicolas S. Buchon, Xiaotian Tang

This study identifies Upd as an activator of JAK/STAT signaling in mosquitoes that restricts arbovirus infection and reduces vector competence.

bioRxiv · Oct 24, 2026 · PreprintMicrobiology

Transcription Factor-Mediated Reprogramming of Cancer-Associated Fibroblasts Reveals Targetable Vulnerabilities in Solid Tumors

Nan Sook Lee, Priyankan Datta, Yixuan Huang, Bella Raykowski, Xi Yu, Tianze Guo, Peixiang He, Sreejesh Moolayadukkam, Ben Yi Tew, Shigang Xiong, Chi Woo Yoon, Yingxiao Wang, Christopher C. DeRenzo, Jacek Pinski, Ishwar K. Puri

This study reprograms cancer-associated fibroblasts using transcription factors to reduce therapy resistance and enhance CAR T cell efficacy in solid tumors.

bioRxiv · Apr 20, 2026 · PreprintCancer Biology

Microglia Regulate Sleep via Calcium-Dependent Modulation of Norepinephrine Transmission

Chenyan Ma, Bing Li, Daniel Silverman, Xinlu Ding, Anan Li, Chi Xiao, Ganghua Huang, Kurtresha Worden, Sandra E. Muroy, Wei Chen, Zhengchao Xu, Chak Foon Tso, Yixuan Huang, Yufan Zhang, Qingming Luo, , Yang Dan

This study shows microglia regulate sleep through Gi-coupled signaling, Ca2+ signaling, and suppression of norepinephrine transmission.

bioRxiv · Jul 24, 2023 · PreprintNeuroscience