Author

Grace Y. Lee

Harvard UniversityORCID 0000-0001-6210-9173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alona MuzikanskyiD· 1 shared Anat O Stemmer-RachamimoviD· 1 shared Athena Ching‐Jung Wang· 1 shared Bo Yuan· 1 shared Chao ZhuiD· 1 shared Gino B. FerraroiD· 1 shared Gizel Askin· 1 shared Gökhan S. HotamışlıgiliD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Alona MuzikanskyORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintJun 9, 2025

Cholesterol-Responsive Interaction of NFE2L1-INSIG1 Controls VLDL Secretion and MASH Pathogenesis

Shijun Deng, Jessica Freed, Grace Y. Lee…·Gökhan S. Hotamışlıgil

This study identifies a cholesterol-responsive interaction between NFE2L1 and INSIG1 that sustains cholesterol balance and prevents MASH by promoting VLDL secretion.

DOI 10.1101/2025.06.09.657856

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 6, 2023

Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain

Zhenzhen Yin, Limeng Wu, Yanling Zhang…·Lei Xu

This study identifies IL-6 and EGFR signaling as therapeutic targets for schwannomatosis, showing combined blockade reduces both pain and tumor growth in preclinical models.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky