Author
Harvard UniversityORCID 0000-0001-6298-7005Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Romi Hadary, Renee B. Chang, Nathalie Béchon…·Rotem Sorek
The paper investigates the functional diversity of phage sponge proteins that sequester host immune signals, identifying new specificities against CBASS, Pycsar, and Thoeris systems.
Mercedes Rivera, Renee B. Chang, Colin M. Lewis…·Philip J. Kranzusch
This study identifies RyDEP as an enzyme that degrades 2'cADPR and 3'cADPR immune signals, inactivating bacterial defense and restoring NAD+.
Nitzan Tal, Romi Hadary, Renee B. Chang…·Rotem Sorek
The paper identifies viral proteins that manipulate bacterial immune signaling by analyzing structural and biophysical traits, and develops a computational pipeline to predict such proteins in phage genomes.
Dziugas Sabonis, Carmel Avraham, Renee B. Chang…·Giedrė Tamulaitienė
The paper identifies His-ADPR as a novel TIR-derived immune signaling molecule in bacteria, showing its role in phage defense and structural basis for recognition.
Renee B. Chang, Hunter C. Toyoda, Samuel J. Hobbs…·Philip J. Kranzusch
The paper identifies Acb4, a viral protein that inhibits bacterial anti-phage defense by sequestering nucleotide signals.