Author

Romi Hadary

Weizmann Institute of Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

Philip J. KranzuschiD· 4 shared Renee B. ChangiD· 4 shared Rotem SorekiD· 4 shared Ilya А. OstermaniD· 3 shared Erez YirmiyaiD· 2 shared Gil AmitaiiD· 2 shared Jeremy GarbiD· 2 shared Mercedes RiveraiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

Philip J. KranzuschORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Functional diversity of phage sponge proteins that sequester host immune signals

Romi Hadary, Renee B. Chang, Nathalie Béchon, Nitzan Tal, Ilya А. Osterman, Erez Yirmiya, Jeremy Garb, Miguel López Rivera, Gil Amitai, Philip J. Kranzusch, Rotem Sorek

The paper investigates the functional diversity of phage sponge proteins that sequester host immune signals, identifying new specificities against CBASS, Pycsar, and Thoeris systems.

Nature Microbiology · Jun 2, 2026Peer-reviewedMicrobiology

Phage RyR-domain proteins degrade ADPR-based immune signals and fuel NAD synthesis

Mercedes Rivera, Renee B. Chang, Colin M. Lewis, Romi Hadary, Julia M. Kovalski, Krista G. Freeman, Zhen-Yu J Sun, Rotem Sorek, Graham F. Hatfull, Philip J. Kranzusch

This study identifies RyDEP as an enzyme that degrades 2'cADPR and 3'cADPR immune signals, inactivating bacterial defense and restoring NAD+.

bioRxiv · May 29, 2026 · PreprintMicrobiology

Structural modeling reveals viral proteins that manipulate host immune signaling

Nitzan Tal, Romi Hadary, Renee B. Chang, Ilya А. Osterman, R.L. Jacobson, Erez Yirmiya, Nathalie Béchon, Dina Hochhauser, Mercedes Rivera, Barak Madhala, Jeremy Garb, Moshe Goldsmith, Tanita Wein, Philip J. Kranzusch, Gil Amitai, Rotem Sorek

The paper identifies viral proteins that manipulate bacterial immune signaling by analyzing structural and biophysical traits, and develops a computational pipeline to predict such proteins in phage genomes.

Science · Mar 5, 2026Peer-reviewedMicrobiology

A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense

Renee B. Chang, Hunter C. Toyoda, Samuel J. Hobbs, Romi Hadary, Desmond Richmond-Buccola, Tanita Wein, Ilya А. Osterman, Nils Burger, Edward T. Chouchani, Rotem Sorek, Philip J. Kranzusch

The paper identifies Acb4, a viral protein that inhibits bacterial anti-phage defense by sequestering nucleotide signals.

Molecular Cell · Dec 31, 2024Peer-reviewedMicrobiology