Author

Franziska L. Sendker

Dana-Farber Cancer InstituteORCID 0000-0001-6311-0539Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Arielle Weinstein· 1 shared Arvind S. PillaiiD· 1 shared Azim M. DharaniiD· 1 shared Brian P. H. MetzgeriD· 1 shared Christopher-Nils MaisiD· 1 shared Daniel SchindleriD· 1 shared Diangen LiniD· 1 shared Eric S. FischeriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

Arielle Weinstein

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 29, 2026

Deep-learning-based design of an orthogonal self-labeling protein from K-Ras(G12C)

Jody Mou, Jing Wesley Leong, Sean Gao…·Nicholas F. Polizzi

This paper designs an orthogonal self-labeling protein, LUCI-tag, using deep learning, which enables rapid and payload-agnostic labeling of proteins in live cells.

DOI 10.64898/2026.09.27.754867

protein structuredeep learning

𝕏 PostBluesky

Evolutionary BiologyNature CommunicationsPeer-reviewedDec 3, 2024

Frequent transitions in self-assembly across the evolution of a central metabolic enzyme

Franziska L. Sendker, Tabea Schlotthauer, Christopher-Nils Mais…·Georg K. A. Hochberg

The paper investigates the evolutionary dynamics of self-assembly in prokaryotic citrate synthases, finding frequent transitions between different assembly types without strong functional consequences.

17 citations

bacteria (other)structural biology

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