Author

Chang Fu Lu

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0001-6331-622XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:Hi-C· 1

Frequent Co-Authors

Anita J HuttneriD· 1 shared Chang LuiD· 1 shared Declan ClarkeiD· 1 shared Donglu Bai· 1 shared Fangdi Xu· 1 shared Hanwen ZhuiD· 1 shared Haowei WangiD· 1 shared Howard S. FoxiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Anita J HuttnerORCID

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2 papers

Recent·Most cited

Exploring multi-level microbial interactions from individual 3D genomes to community networks

Wen-Jie Jiang, Kang-Wen Cai, Yuanchen Sun, Zhetao Zheng, Fangdi Xu, Rui-Xiang Gao, Nana Wei, Hanwen Zhu, Wang Yu-Juan, Qing Xia, Chang Lu, Chang Fu Lu, Hua‐Jun Wu

This study introduces FindMeta3D to analyze microbial 3D genomes and cross-domain interactions, revealing conserved chromatin patterns and infection-related hotspots with therapeutic implications.

bioRxiv · Dec 4, 2025 · PreprintMicrobiology

Multi-omic Characterization of HIV Effects at Single Cell Level across Human Brain Regions

Junchen Yang, Kriti Agrawal, Jay S. Stanley, Ruiqi Li, Nicholas Jacobs, Haowei Wang, Chang Fu Lu, Rihao Qu, Declan Clarke, Yuhang Chen, Yunzhe Jiang, Donglu Bai, Suchen Zheng, Howard S. Fox, Ya‐Chi Ho, , Serena Spudich

This study uses single-nucleus multiome sequencing to identify HIV-associated transcriptional and epigenetic changes in brain regions of individuals with HIV, revealing altered glial cell states and pro-inflammatory signaling.

bioRxiv · Feb 5, 2025 · PreprintBioinformatics