Noga Ron‐Harel

Haem toxicity in the aged spleen impairs T-cell immunity through iron deprivation

This study shows that haem toxicity in the aged spleen impairs T-cell immunity through iron deprivation, and iron infusions can enhance vaccination responses in aged mice.

An Aged Microenvironment Increases CAR T Cell Cytotoxicity but Impairs Therapeutic Efficacy

This study shows that aging affects CAR T cell production and function, leading to reduced therapeutic efficacy in elderly hosts.

In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and Autoimmunity

The paper introduces Compass, an algorithm that uses single-cell RNA-Seq and flux balance analysis to characterize metabolic states in Th17 cells, revealing a metabolic switch and novel anti-inflammatory regulators.