Evgenia Ntini

The paper identifies PVT1 splicing activity as a predictor of gene expression signatures enriched in miR-200/205 targets in breast cancer.

The paper shows hypoxia reduces EXOSC10 SUMOylation, leading to its nuclear translocation and changes in mRNA transcriptome related to hypoxia.

The paper identifies distal and proximal cis-regulatory elements that respond to X-chromosomal dosage and developmental state to regulate Xist expression during XCI in mouse embryonic stem cells.

The paper models lncRNA chromatin (dis-)association using nascent RNA sequencing and identifies factors influencing dissociation and its functional impact.

This paper presents a high-sensitivity targeted method to measure pri-miRNA processing efficiency in clinical samples and identifies 24 microRNAs with significant changes in processing efficiency between normal liver and hepatocellular carcinoma.

The paper develops a graph analysis method combining co-expression and ChIA-PET data to identify lncRNA-mediated regulatory modules in K562 cells, finding enriched disease associations and functional roles for lncRNAs.

The paper investigates the role of m6A in splicing efficiency by analyzing nascent RNA transcripts and shows that early m6A deposition accelerates splicing.

The paper identifies A-ROD as a long ncRNA that requires chromatin-release to activate DKK1 transcription by recruiting EBP1 to the promoter.

The paper develops a method to study pri-miRNA processing kinetics in vivo and shows co- and post-transcriptional processing occurs with varying speeds.