Author

Francesca Simonetti

Johannes Gutenberg University MainzORCID 0000-0001-6437-8879Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Ali RezaeiiD· 1 shared Anusha B. GopalaniD· 1 shared Dieter EdbaueriD· 1 shared Dorothee DormanniD· 1 shared Federico UlianaiD· 1 shared Fridolin KielischiD· 1 shared Henrick RiemenschneideriD· 1 shared Janine HochmairiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ali RezaeiORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJul 7, 2025

Direct binding of TDP-43 and Tau drives their co-condensation, but suppresses Tau fibril formation and seeding

Francesca Simonetti, Weijia Zhong, Saskia Hutten…·Dorothee Dormann

This study shows that TDP-43 and Tau directly interact, promoting co-condensation but reducing Tau fibril formation and seeding.

1 citation

humanproteomics

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