Author
University of MinhoORCID 0000-0001-6441-0285Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Daniela Vilasboas‐Campos, Jorge H. Fernandes, M. C. M. M. Michelle Cristina Magalhàes Melgaço Costa Costa…·Andreia Teixeira‐Castro
This paper introduces PRO-FitS, a C. elegans-based phenotypic assay to identify proteostasis enhancers, validated through mTOR inhibition and serotonergic signaling effects on heat shock-induced proteotoxicity.
Alexandra Silva, Sara Duarte‐Silva, Pedro Miguel Martins…·Sandra Macedo‐Ribeiro
This study shows that CLR01, a supramolecular tweezer, reduces Atx3 aggregation by binding to a specific site, delaying fibril formation and improving symptoms in SCA3 models.
Bruna Ferreira-Lomba, Sara R. Guerreiro, Sara Duarte‐Silva…·Patrı́cia Maciel
This study evaluates NLX-112, a 5-HT1A receptor agonist, in a mouse model of SCA3, showing improved motor function and neuroprotection when administered pre-symptomatically.