Author

Sjoerd J. L. van Wijk

Goethe University FrankfurtORCID 0000-0001-6532-7651Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Alec Geßner· 1 shared Andreas WeigertiD· 1 shared Ernst H. K. StelzeriD· 1 shared Francesco PampaloniiD· 1 shared Geoffroy AndrieuxiD· 1 shared Ivan-Maximilano KuriD· 1 shared Jana V. Schneider· 1 shared Kaja Nicole WächtershäuseriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alec Geßner

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1 paper

Recent·Most cited

Cancer BiologySignal Transduction and Targeted TherapyPeer-reviewedJun 1, 2026

Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

Kaja Nicole Wächtershäuser, Jana V. Schneider, Alec Geßner…·Sjoerd J. L. van Wijk

This study shows that Smac mimetics induce apoptosis in breast cancer organoids and that necroptosis, associated with inflammation, can be inhibited by LUBAC inhibitors.

1 citation

humanorganoid / primary culture

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