Author

Yew Yan Wong

The University of SydneyORCID 0000-0001-6557-4492Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Mathias FrançoisiD· 4 shared Matthew S. GrausiD· 4 shared Bitong LiiD· 2 shared Elizabeth HindeiD· 2 shared Jieqiong LouiD· 2 shared Susav PradhaniD· 2 shared Tara Davidson· 2 shared Winnie LuuiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersMolecular Biology

Mathias FrançoisORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 28, 2025

Oncogenic virus hijacks SOX18 pioneer function to enhance viral persistence

Krista Tuohinto, Matthew S. Graus, Peyton Staab…·Päivi M. Ojala

This study shows KSHV uses SOX18 to maintain viral episomes in LECs by enhancing chromatin accessibility.

2 citations

humanDNA methylation

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Developmental BiologybioRxivPreprintApr 25, 2025

Biophysical dissection of SOX18/NR2F2 transcriptional antagonism reveals mechanisms of venous differentiation and drug action in vascular malformation

Matthew S. Graus, Sawan Kumar Jha, Jieqiong Lou…·Mathias François

This study identifies a biophysical mechanism of SOX18/NR2F2 transcriptional antagonism that governs venous differentiation and shows that inhibiting SOX18 can improve vascular malformation symptoms.

DOI 10.1101/2025.04.25.650344

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintSep 10, 2024

RNA-mediated SOX2 temporal dynamics govern dual chromatin engagement modes at Nanog

Bitong Li, Yew Yan Wong, Yoshiaki Kobayashi…·Mathias François

The paper uses single-molecule imaging to show RNA fluctuations modulate SOX2 dynamics at the Nanog locus, revealing RNA-dependent feedback in transcriptional regulation.

1 citation

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Developmental BiologyThe EMBO JournalPeer-reviewedJan 30, 2023

The blood vasculature instructs lymphatics patterning in a SOX7-dependent manner

Ivy Kim Chiang, Matthew S. Graus, Nils Kirschnick…·Mathias François

This study identifies SOX7 as a transcription factor in blood vascular endothelial cells that represses Vegfc expression, influencing lymphatic vessel patterning in mice.

11 citations

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