Matthew S. Graus

The paper shows that Piezo1 mediates fluid shear stress-induced nuclear remodeling and chromatin reorganization in endothelial cells by linking cytoplasmic and nuclear mechanotransduction.

This study shows KSHV uses SOX18 to maintain viral episomes in LECs by enhancing chromatin accessibility.

This study identifies a biophysical mechanism of SOX18/NR2F2 transcriptional antagonism that governs venous differentiation and shows that inhibiting SOX18 can improve vascular malformation symptoms.

The paper identifies a SOX18-mevalonate pathway axis in infantile hemangioma and suggests repurposing statins as a treatment.

The paper uses single-molecule imaging to show RNA fluctuations modulate SOX2 dynamics at the Nanog locus, revealing RNA-dependent feedback in transcriptional regulation.

This study identifies SOX7 as a transcription factor in blood vascular endothelial cells that represses Vegfc expression, influencing lymphatic vessel patterning in mice.