Author

Nestor Nivardo Jiménez-Vargas

New York UniversityORCID 0000-0001-6595-1884Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Badr SokratiD· 2 shared Brian L. SchmidtiD· 2 shared Nigel W. BunnettiD· 2 shared Stephen J. VanneriD· 2 shared Abby Mocherniak· 1 shared Alan E. LomaxiD· 1 shared Chloe J. PeachiD· 1 shared Dane D. JenseniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Badr SokratORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 2, 2026

ENDOSOMAL SIGNALING OF PROTEASE-ACTIVATED RECEPTOR-2 AMPLIFIES HISTAMINE-INDUCED PAIN OF IRRITABLE BOWEL SYNDROME

Nestor Nivardo Jiménez-Vargas, Badr Sokrat, Daniella A Gilmour…·Nigel W. Bunnett

This study shows that PAR2 endosomal signaling amplifies and sustains histamine-induced pain in IBS by maintaining H1R activity.

DOI 10.64898/2026.01.30.702691

𝕏 PostBluesky

PhysiologyProceedings of the National Academy of SciencesPeer-reviewedOct 7, 2025

Nanomedicines targeting signaling of protease-activated receptor 2 in organelles provide sustained analgesia

Shavonne L. Teng, Rocco Latorre, Divya Bhansali…·Nigel W. Bunnett

This study shows that targeting protease-activated receptor 2 (PAR2) signaling in organelles using nanomedicines provides sustained analgesia in preclinical models of inflammatory bowel disease.

13 citations

𝕏 PostBluesky