Son Pham

This study shows that BTP2 inhibits Tulane virus and human norovirus replication by targeting structural proteins, not through SOCE, and establishes a system for antiviral screening.

This study identifies conformational flexibility in GII proteases as a key factor affecting inhibitor potency, guiding the design of broad-spectrum norovirus protease inhibitors.

Venice identifies marker genes in single-cell data by distinguishing cell populations using a new metric, outperforming existing methods in speed and accuracy.

The paper introduces a low-cost, high-accuracy method for generating long-range sequencing data using short-read NGS systems, enabling de novo genome assembly and haplotype phasing with minimal DNA input.

Hera-T improves gene abundance quantification in 10X-Chromium data by reducing runtime and memory use while maintaining accuracy compared to Cell Ranger.

This paper revises the RSEM EM algorithm to improve quantification speed while maintaining accuracy, introducing optimizations and parameter convergence strategies.

The paper introduces Ragout, a reference-assisted assembly tool that improves chromosome assembly for large and complex genomes, achieving high accuracy with less than 5% unlocalized sequence.

The paper compares genome assemblies of Mus caroli and Mus pahari with Mus musculus and Rattus norvegicus to reveal lineage-specific evolutionary mechanisms, particularly repeat-associated processes.

The paper improves the American alligator genome assembly and identifies estrogen-responsive regions linked to female-biased gene expression in post-temperature-sensitive gonads.