Author

B. V. Venkataram Prasad

Baylor College of MedicineORCID 0000-0002-1172-2071Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:structural biology· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Mary Kolb EstesiD· 4 shared Janam J. DaveiD· 3 shared Khalil EttayebiiD· 2 shared Robert L. AtmariD· 2 shared S. H. PhamiD· 2 shared Sasirekha RamaniiD· 2 shared Soni KaundaliD· 2 shared Sue E. CrawfordiD· 2 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersMicrobiology

Mary Kolb EstesORCID

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Author profile →

4 papers

Recent·Most cited

Mutational Analysis of Human Norovirus VP2 Elucidates Critical Molecular Interactions for Virus Assembly

Janam J. Dave, Sue E. Crawford, Robert L. Atmar, Khalil Ettayebi, B. V. Venkataram Prasad, Mary Kolb Estes

This paper identifies critical molecular interactions of VP2 in HuNoV assembly through mutational analysis and computational modeling.

Journal of Virology · Dec 30, 2025Peer-reviewedMicrobiology

Functional Diversity in GII.4 Norovirus Entry: HBGA Binding and Capsid Clustering Dynamics

B. Vijayalakshmi Ayyar, Carmen V. Apostol, Janam J. Dave, Soni Kaundal, Joseph A. Kendra, Frederick H. Neill, Khalil Ettayebi, Sarah Maher, Ramakrishnan Anish, Gabriel Ignacio Parra, Göran Larson, Robert L. Atmar, Sue E. Crawford, B. V. Venkataram Prasad, Mary Kolb Estes

The paper compares GII.4 norovirus variants to determine if clustering and entry mechanisms are conserved, finding clustering enhances entry and is mediated by specific residues and lipid rafts.

Proceedings of the National Academy of Sciences · Oct 1, 2025Peer-reviewedMicrobiology

The Orai channel inhibitor BTP2 restricts Tulane virus and human norovirus replication independent of store-operated calcium entry

Francesca J. Scribano, John Thomas Gebert, Kristen A. Engevik, Nicole M. Hayes, Son Pham, Soni Kaundal, Janam J. Dave, B. V. Venkataram Prasad, Mary Kolb Estes, Sasirekha Ramani, Joseph M. Hyser

This study shows that BTP2 inhibits Tulane virus and human norovirus replication by targeting structural proteins, not through SOCE, and establishes a system for antiviral screening.

bioRxiv · Feb 23, 2025 · PreprintMicrobiology

Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors

S. H. Pham, Boyang Zhao, Neetu Neetu, Banumathi Sankaran, Ketki Patil, Sasirekha Ramani, Yongcheng Song, Mary Kolb Estes, Timothy Gerald Palzkill, B. V. Venkataram Prasad

This study identifies conformational flexibility in GII proteases as a key factor affecting inhibitor potency, guiding the design of broad-spectrum norovirus protease inhibitors.

Journal of Virology · Jan 28, 2025Peer-reviewedBiochemistry