María Betina Pampena

This study shows fractalkine-conjugated mRNA-LNP can target and modify CD8+ T cells in vivo, enabling transient expression of proteins like IL-2 and CD62L.

This study identifies a noncanonical PRDM1+ Tfh subset selectively depleted in HIV viremia but recoverable under ART, highlighting its susceptibility to infection and implications for HIV reservoirs.

This study identifies disrupted lymphocyte chemotaxis in idiopathic multicentric Castleman disease, linking dysregulated chemokine production to germinal center dysfunction and lymphadenopathy.

This study shows that retaining CD8+ T cells in lymphoid tissues during ART interruption does not prevent SIV rebound, even with immunomodulators.

The paper analyzes immune cell changes in human pancreas-draining lymphatic tissues before and after T1D onset, identifying proinflammatory patterns and genetic risk correlations.