Author

Marco Vincenzo Russo

University of MiamiORCID 0000-0002-5148-1305Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Abdessamad Youssfi AlaouiiD· 1 shared Alexa Marie BarrosoiD· 1 shared Alexandra Marie CarboneiD· 1 shared Alicia Bilbao MartineziD· 1 shared Austin Daniel NewsamiD· 1 shared Charles L. SawyersiD· 1 shared Daniel BilbaoiD· 1 shared Dhanvantri ChahariD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Abdessamad Youssfi AlaouiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy

Paola Manara, Austin Daniel Newsam, Venu Venkatarame Gowda Saralamma, Tyler Andrew Cunningham, Drew Lazenby, J.J.David Ho, Marco Vincenzo Russo, Abdessamad Youssfi Alaoui, Dhanvantri Chahar, Alicia Bilbao Martinez, Nikolai S. Fattakhov, Alexandra Marie Carbone, Olivia Barbara Farag, Alexa Marie Barroso, Kyle S. Hoffman, , Jonathan Harry Schatz

This study shows that inhibiting cap-dependent translation in lymphoma cells increases sensitivity to ferroptosis and CAR-T therapy by reducing NRF2 expression.

Cancer Research · Jul 31, 2025Peer-reviewedCancer Biology

BRCA2 reversion mutation-independent resistance to PARP inhibition in prostate cancer through loss of function perturbations in the DNA pre-replication complex

Kyrie Pappas, Matteo Ferrari, Perianne Smith, Subhiksha Nandakumar, Zahra Khan, Serina B Young, Justin R. LaClair, Marco Vincenzo Russo, Emmet Huang-Hobbs, Nikolaus D. Schultz, Wassim M. Abida, Wouter R. Karthaus, Maria Jasin, Charles L. Sawyers

This study identifies loss of function mutations in the DNA pre-replication complex as a mechanism for PARP inhibitor resistance in BRCA-mutant prostate cancer, independent of reversion mutations.

bioRxiv · Apr 20, 2025 · PreprintCancer Biology