Hemant Mahendrakumar Kocher

This study benchmarks three low-input whole exome sequencing workflows for ctDNA profiling in PDAC, showing Agilent V8 provides best performance in low-input settings.

This paper identifies long deletion signatures in repetitive regions as markers of microsatellite instability and develops a classifier to detect MSI in low-quality sequencing data.

The paper identifies non-coding mutations in enhancer clusters associated with pancreatic ductal adenocarcinoma and validates their functional impact using computational and experimental methods.