Jorine M. Eeftens

This study quantifies how CpG methylation affects chromatin mechanics, nucleosome wrapping, and condensate properties across multiple scales.

This study investigates how amyloidogenic proteins like synuclein adsorb to biomolecular condensates and how this process can be modulated to slow aggregation.

This study develops a mesoscopic model showing how condensates interact with chromatin through elastocapillary forces, influencing chromatin organization and function.

This study develops a method using optical tweezers to accurately measure cellular mechanics, showing sensitivity to cytoskeleton perturbations.

This study investigates how BRD4 chromatin binding modulates its condensate formation, showing that chromatin interactions influence both kinetic and thermodynamic properties of BRD4 condensation.

The paper investigates the role of liquid-liquid phase separation in transcriptional repression by studying Hes/Gro complexes in Ciona embryos and their behavior during cell cycles.

This study shows that condensin complexes use opposing ATPase sites to drive and dampen chromosome condensation, with condensin II playing a key role in decatenation and axis formation.