Author
The Netherlands Cancer InstituteORCID 0000-0002-0694-8463Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Jaco van der Torre, Roman Barth, Klaudia Majszczyk, Thejas Satheesh, Brian T. Analikwu, Clément Rouillon, Eva Bertosin, Benjamin D. Rowland, Cees Dekker
The paper introduces a modular DNA toolkit for creating long, customizable DNA molecules with user-defined sequences for single-molecule biophysics applications.
bioRxiv · Oct 10, 2026 · PreprintBiophysics
Anoek Friskes, Melanie Snoek, Lisa Koob, Roel Oldenkamp, Bram van den Broek, Leila Nahidiazar, Lukas Frank, Amalie E. Dick, Marjolijn Mertz, Rolf Harkes, Benjamin D. Rowland, Kees Jalink, René H. Medema
This study visualizes homology search dynamics in living human cells using GFP-MND1, revealing filament structures that resolve over time and depend on RAD54L and cohesin.
Nucleic Acids Research · Aug 25, 2026Peer-reviewedCell Biology
Alessandro Borsellini, Duccio Conti, Erin Cutts, Rebecca J. Harris, Kai Walstein, Andrea Graziadei, Valentina Cecatiello, Tom F. Aarts, Ren Xie, Abdelghani Mazouzi, Sushweta Sen, Claire Hoencamp, Richard Pleuger, Sabrina Ghetti, Lina Oberste-Lehn, , Alessandro Vannini
The paper identifies M18BP1 as a factor required for condensin II localization to chromatin and shows it competes with MCPH1 to activate condensin II during mitosis.
Molecular Cell · Jul 1, 2025Peer-reviewedCell Biology
Stefano Giustino Manzo, Abdelghani Mazouzi, Christ Leemans, Tom van Schaik, Nadia Neyazi, Marjon S. van Ruiten, Benjamin D. Rowland, Thijn R. Brummelkamp, Bas van Steensel
The paper identifies chromatin regulators involved in gene repression in lamina-associated domains (LADs) through genetic screens, showing that transcription elongation and chromatin remodeling factors, not nuclear lamina proteins, mediate repression.
The EMBO Journal · Sep 25, 2024Peer-reviewedMolecular Biology
Robin H. van der Weide, Teun van den Brand, Judith H.I. Haarhuis, Hans Teunissen, Benjamin D. Rowland, Elzo de Wit
GENOVA is an R-package for analysing Hi-C data, demonstrating that cohesin subunits SA1 and SA2 differentially affect loop formation and genome compartmentalisation.
NAR Genomics and Bioinformatics · Apr 9, 2021Peer-reviewedGenomics
Ahmed M.O. Elbatsh, Eugene Kim, Jorine M. Eeftens, Jonne A. Raaijmakers, Robin H. van der Weide, Alberto García-Nieto, Sol Bravo, Mahipal Ganji, Jelmi uit de Bos, Hans Teunissen, René H. Medema, Elzo de Wit, Christian H. Haering, Cees Dekker, Benjamin D. Rowland
This study shows that condensin complexes use opposing ATPase sites to drive and dampen chromosome condensation, with condensin II playing a key role in decatenation and axis formation.
Molecular Cell · Oct 16, 2019Peer-reviewedMolecular Biology
Amin Allahyar, Carlo Vermeulen, Britta A. M. Bouwman, Peter H.L. Krijger, Marjon J.A.M. Verstegen, Geert Geeven, Melissa van Kranenburg, Mark Pieterse, Roy Straver, Judith H.I. Haarhuis, Kees Jalink, Hans Teunissen, Ivo Renkens, Wigard P. Kloosterman, Benjamin D. Rowland, , Wouter L. de Laat
The paper introduces a new 3C method, MC-4C, to study multi-way DNA conformations and reveals cooperative and competitive chromatin interactions, including enhancer hubs and loop collisions.
Nature Genetics · Jul 6, 2018Peer-reviewedGenetics