James W. Opzoomer

This paper introduces PEP-seq, a method linking genetic variants to transcriptomic states, and shows it can detect functional effects of eQTLs and nonsense-mediated decay.

SIGNAL-seq measures RNA and PTMs in single cells to analyze inter- and intra-cellular signaling in the tumor microenvironment.

ImmunoCluster provides an R package for analyzing high-dimensional cytometry data, enabling non-specialists to profile cellular heterogeneity through scalable analysis and visualization tools.

This paper develops hypoxia-sensing CAR T-cells that selectively target solid tumors without off-tumor toxicity using murine xenograft models.