Author

Jahangir Sufi

University College LondonORCID 0000-0002-4563-5531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Christopher J. TapeiD· 3 shared Ralitsa Radostinova MadseniD· 2 shared Xiao QiniD· 2 shared Alix Le MaroisiD· 1 shared Bart VanhaesebroeckiD· 1 shared Brendan C. JonesiD· 1 shared Camilla LuniiD· 1 shared D. Morelli· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

Christopher J. TapeORCID

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3 papers

Recent·Most cited

Human Gastric Multi-Regional Assembloids Favour Functional Parietal Maturation and Allow Modelling of Antral Foveolar Hyperplasia

Brendan C. Jones, Giada Benedetti, Giuseppe Calà, Ramin Amiri, Lucinda Tullie, Roberto Lutman, Jahangir Sufi, Lucy Holland, Daniyal J. Jafree, Monika Bałys, Glenn W. Anderson, Ian C. Simcock, Owen John Arthurs, Simon D. Eaton, Nicola Elvassore, , Paolo De Coppi

The paper develops multi-regional gastric assembloids from patient-derived organoids to model parietal cell maturation and antral foveolar hyperplasia in genetic disorders.

Nature Biomedical Engineering · Jan 23, 2026Peer-reviewedCell Biology

SIGNAL-seq: Multimodal Single-cell Inter- and Intra-cellular Signalling Analysis

James W. Opzoomer, Rhianna O’Sullivan, Jahangir Sufi, Ralitsa Radostinova Madsen, Xiao Qin, Ewa Basiarz, Christopher J. Tape

SIGNAL-seq measures RNA and PTMs in single cells to analyze inter- and intra-cellular signaling in the tumor microenvironment.

bioRxiv · Feb 23, 2024 · PreprintCancer Biology

Oncogenic PIK3CA corrupts growth factor signaling specificity

Ralitsa Radostinova Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, S. Yin, Jahangir Sufi, Xiao Qin, Salome Jingchen Zhao, Julia Górczyńska, D. Morelli, L. Davidson, Erik A. Sahai, Viktor I. Korolchuk, Christopher J. Tape, Bart Vanhaesebroeck

The paper uses single-cell analyses to show that oncogenic PIK3CAH1047R reduces IGF1 signaling specificity and enhances EGF responses, leading to increased phenotypic heterogeneity.

bioRxiv · Dec 23, 2023 · PreprintSystems Biology