PIEZO-dependent mechano-sensing of the niche is essential for intestinal stem cell fate decision and maintenance
Meryem B. Baghdadi, Ronja M. Houtekamer, Louisiane Perrin, Abilasha Rao‐Bhatia, Myles Whelen, Linda Decker, Martin Bergert, Carlos Perez Gonzalez, Réda Bouras, Giacomo Gropplero, Adrian Kwan Ho Loe, Amin Afkhami-Poostchi, Xin Chen, Xi Huang, Stéphanie Descroix, , Tae-Hee Kim
This study shows PIEZO channels are essential for intestinal stem cell maintenance by sensing mechanical cues from their niche.
Science · Nov 28, 2024Peer-reviewedCell Biology