Boris Pfander

The paper identifies DDK-mediated phosphorylation of INO80's Arp8 subunit, which stabilizes the complex and regulates nucleosome spacing at replication origins, enhancing replication efficiency and stress response.

The paper identifies proto-point centromeres in Saccharomycodales yeast, showing they evolved from retrotransposon LTRs, supporting the hypothesis that point centromeres originated from ancestral retrotransposons.

The paper induces unscheduled DNA replication in G1-phase budding yeast, showing it leads to genome instability through head-to-tail replication fork collisions during subsequent S-phase.

The paper shows that DNA damage triggers rDNA repeat relocation by phosphorylating the CLIP-cohibin complex, leading to SUMOylation and Cdc48/p97-mediated release from the nucleolus in yeast and human cells.