Haoyu Wang

This study examines how altered medial olivocochlear (MOC) activity affects synaptic structure and function in the auditory brainstem using mouse models.

This study shows that variations in Ca2+ channel activation in inner hair cells affect spiral ganglion neuron firing rates and sound threshold, with implications for noise-induced hearing loss in patients with the CaV1.3A749G mutation.

This study shows noise-induced synaptopathy disproportionately affects long and short sensory hair cells in the mammalian cochlea, with distinct spatial patterns of ribbon synapse loss.

The paper reconstructs neural circuitry in the mouse cochlea using electron microscopy, showing differences in efferent innervation of spiral ganglion neurons based on their synaptic connectivity with inner hair cells.