David Ryan Ormond

This study shows estradiol suppresses microglial immunity and promotes breast cancer brain metastasis, with E2 suppression enhancing anti-tumor responses and synergizing with radiotherapy.

This study shows that NTRK inhibitors can reduce brain metastases in lung cancers with wild-type NTRK, even without NTRK fusions.

This study identifies genetic changes in IDH-mutant gliomas that correlate with treatment response and tumor evolution using longitudinal genomic data from 206 patient samples.

This study analyzes the epigenetic evolution of IDH1-mutant and IDH1-wildtype gliomas under treatment, showing IDHmut tumors undergo epigenomic changes resembling IDHwt tumors, with implications for treatment strategies.