Florent C. Mouliere

Ouro-seq improves full-length circRNA recovery from low-RNA samples, revealing distinct circRNA types and functions in clinical contexts.

This paper introduces NanoRCS, a method using nanopore sequencing and consensus calling to accurately estimate tumor fractions from cfDNA by analyzing SNVs, CNAs, and fragmentomics.

The paper shows that EV-DNA in lung cancer patients is not enriched in tumor signal compared to plasma cfDNA, with similar fragmentation and tumor content.

This study examines how pre-analytical and physiological factors affect cfDNA fragmentation patterns and fragment-end sequences using whole genome sequencing.

This study identifies and integrates three genome-wide features of cfDNA fragmentation to enhance ctDNA detection in ovarian cancer patients.

The paper detects circulating tumor DNA in plasma and urine of glioma patients using sequencing guided by tumor mutations.

The paper shows that selecting short DNA fragments in plasma improves the detection of circulating tumour DNA by enriching mutated DNA, enabling identification of copy number alterations previously undetected.