Author

Elizabeth K. Moore

University of CambridgeORCID 0000-0002-2728-3202Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

James D. BrentoniD· 3 shared A. M. PiskorziD· 2 shared Christopher G. SmithiD· 2 shared Dineika ChandranandaiD· 2 shared Florent C. MouliereiD· 2 shared James Morris· 2 shared Nitzan RosenfeldiD· 2 shared Teodora GoranovaiD· 2 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

James D. BrentonORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 15, 2024

Primary culture of high grade serous ovarian cancer cells, selection and derivation of three cell lines

James D. Brenton, Maria Vias, Carolin M. Sauer…·Ian S. Goldlust

The paper generates and characterizes three new HGSOC cell lines that retain genomic and pathologic features of their parental tumors, providing models for studying chemoresistance.

2 citations

humanorganoid / primary culture

𝕏 PostBluesky

Genetic & Genomic MedicineScientific ReportsPeer-reviewedFeb 4, 2022

Refined characterization of circulating tumor DNA through biological feature integration

Havell Markus, Dineika Chandrananda, Elizabeth K. Moore…·Nitzan Rosenfeld

This study identifies and integrates three genome-wide features of cfDNA fragmentation to enhance ctDNA detection in ovarian cancer patients.

56 citationstop 2%

humanwhole-genome sequencing

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GenomicsbioRxivPreprintMay 5, 2017

Selecting Short DNA Fragments In Plasma Improves Detection Of Circulating Tumour DNA

Florent C. Mouliere, Anna Piskorz, Dineika Chandrananda…·Nitzan Rosenfeld

The paper shows that selecting short DNA fragments in plasma improves the detection of circulating tumour DNA by enriching mutated DNA, enabling identification of copy number alterations previously undetected.

26 citations

humanDNA methylation

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