Marcel Mettlen

This paper develops an in vitro model of complex flow patterns using engineered geometries and computational fluid dynamics to study endothelial cell adaptation to hemodynamic forces.

The paper identifies METEORs, mitochondria specialized for filopodia, and shows their role in supporting cellular migration.

This study identifies ZNF692 as a nucleolar scaffold that enhances 40S ribosome maturation and translation efficiency in rapidly proliferating cells, particularly in cancer cells.