Chenyu Wang

This study investigates the distinct roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability using inhibitors and genetic modifications to selectively block each isoform.

The paper identifies Inflares, spatiotemporally selective ATP events from astrocytes, which encode injury information and guide microglial response, showing their role in both injury amplification and therapeutic reversal.

This study shows that intralaminar and medial thalamic nuclei, not the prefrontal cortex, transiently gate conscious perception through thalamocortical synchronization and theta phase modulation.

The paper identifies impaired cerebellar plasticity as a mechanism underlying hypersensitized sensory reflexes in SCN2A-associated ASD, showing that increasing Scn2a expression rescues VOR plasticity in mice.