Evgeny Kanshin

This study shows that tRNA modification mcm5s2U34 is essential for stress granule formation and melanoma metastasis, suggesting it as a therapeutic target.

This study shows FGL-1 binding to LAG-3 inhibits T cell activation by disrupting CD28 and TCR signaling through Lck mislocalization and reduced phosphorylation.

The paper identifies proteomic differences in epilepsy brain tissue, highlighting altered protein networks in hippocampus, cortex, and dentate gyrus, with GNB1 as a key decreased protein.

The paper compares proteomic and transcriptomic profiles of hippocampus and cortex in SUDEP and high-risk SUDEP cases, finding no proteomic differences but 55 differentially expressed genes in hippocampus.