Hans Tobias Gustafsson

This study benchmarks the OTTR protocol for characterizing tRNAs and tRNA fragments in yeast and mouse, showing its accuracy and revealing new insights into sperm small RNA content.

The paper investigates the functional differences between Ssa4 and Ssa1/2 Hsp70s in yeast, showing Ssa4 can compensate for Ssa1/2 loss in some aspects of protein quality control but not all, and that Hsp104-dependent aggregate clearance is not essential for longevity.