Integration of Neuroimaging and Histopathology in a Squirrel Monkey Model of Spontaneous Cerebral Amyloid Angiopathy and Amyloid-Related Imaging Abnormalities
Youssef Zaim Wadghiri, Suleiman Khan, Muhammad T Soliman, Jakub Szabó, Audrey Murray, Akash G. Patel, Charles Kingsley, Jody Swain, Pramod N. Nehete, Jelle Veraart, Michele Marie Mulholland, William Donald Hopkins, Thomas Wısnıewskı, Henrieta Scholtzova
This study uses MRI and histopathology in squirrel monkeys to link R2* changes with CAA severity and ARIA-related tissue injury, supporting early detection and treatment strategies.
bioRxiv · Oct 13, 2026 · PreprintNeuroscience