Anant K. Paravastu

This paper develops a detergent-free method to produce Aβ42 oligomers compatible with solid-state NMR and shows they induce stronger microglial inflammation than monomers.

This study investigates how deamidation at Q15 or N27 in Aβ-42 affects its aggregation and microglial immune response, finding reduced inflammation and altered CD68 expression.

This study examines the aggregation dynamics of a 150 kDa Aβ42 oligomer using cryo-EM and other techniques, revealing unique string-like assemblies distinct from classical fibrils.

This study investigates the role of cysteine residues in biomolecular condensates, showing they function as covalent nodes that tune phase separation through redox-sensitive disulfide bonds.

The paper identifies the sequence S331-G-S-L334 within the amyloid core of myocilin fibrils using low-resolution 3D solid-state NMR.