Author

Marco Barone

Stony Brook UniversityORCID 0000-0001-7184-2940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian WhittyiD· 1 shared Amanda L. WaterburyiD· 1 shared Ana CorrioneroiD· 1 shared Andrea MatteviiD· 1 shared Anza Suneer Rahiyanath· 1 shared Bharath SrinivasaniD· 1 shared Brian B. LiauiD· 1 shared Ceejay LeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Adrian WhittyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 22, 2026

Protein-ligand binding kinetics are primarily controlled by the protein, not the ligand.

Bharath Srinivasan, Ana Corrionero, Marco Barone…·Peter J. Tonge

The paper analyzes 4,311 protein-small-molecule interactions to show that binding kinetics are mainly controlled by protein dynamics, not ligand structure.

DOI 10.64898/2026.05.20.726507

proteomicsstatistical model

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Molecular BiologyNaturePeer-reviewedFeb 12, 2025

Asymmetric Engagement of Dimeric CRL3KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes

Megan J. R. Yeo, Olivia Zhang, Xiaowen Xie…·Ning Zheng

This paper identifies UM171 as a molecular glue that promotes degradation of HDAC1/2 complexes by inducing asymmetric interactions between KBTBD4 and HDAC1.

59 citationstop 1%

humanproteomics

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