Author

Adrian Whitty

Boston UniversityORCID 0000-0002-0331-4369Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:clustering· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ana CorrioneroiD· 1 shared Anastasiya BuzukiD· 1 shared Anthony M. DeMaria· 1 shared Anza Suneer Rahiyanath· 1 shared Bharath SrinivasaniD· 1 shared Christopher J. DiRussoiD· 1 shared Deborah L. PerlsteiniD· 1 shared Jack J. JordanidesiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Ana CorrioneroORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Protein-ligand binding kinetics are primarily controlled by the protein, not the ligand.

Bharath Srinivasan, Ana Corrionero, Marco Barone, Patricia Alfonso, Niall Prendiville, Tatiana Cazorla, Anza Suneer Rahiyanath, Adrian Whitty, Peter J. Tonge

The paper analyzes 4,311 protein-small-molecule interactions to show that binding kinetics are mainly controlled by protein dynamics, not ligand structure.

bioRxiv · May 22, 2026 · PreprintBiochemistry

Getting Started with Machine Learning for Experimental Biochemists and Other Molecular Scientists

Matthew J. K. Vince, Kristin A. Hughes, Anastasiya Buzuk, Deborah L. Perlstein, Lauren A. Viarengo‐Baker, Adrian Whitty

This paper provides step-by-step tutorials on four machine learning methods for experimental molecular scientists without prior ML or coding experience.

Current Protocols · Apr 1, 2025Peer-reviewedBiochemistry

A Conserved Core Region of the Scaffold NEMO is Essential for Signal-induced Conformational Change and Liquid-liquid Phase Separation

Christopher J. DiRusso, Anthony M. DeMaria, Judy Wong, Wei Wang, Jack J. Jordanides, Adrian Whitty, Karen N. Allen, Thomas D. Gilmore

This study identifies a conserved core region in NEMO essential for conformational changes and liquid-liquid phase separation in the NF-κB signaling pathway.

Journal of Biological Chemistry · Oct 27, 2023Peer-reviewedMolecular Biology