Florian Donneger

This study identifies two compounds that enhance KCC2 function, reducing interictal activity and preventing seizures in mesial temporal lobe epilepsy.

This study investigates chloride regulation by cation-chloride cotransporters in mouse hippocampal parvalbumin interneurons and pyramidal cells, showing similar mechanisms and the critical role of KCC2 in maintaining inhibitory GABA signaling.

This study shows that KCC2 downregulation in rat dentate gyrus leads to increased neuronal excitability and altered network activity through interactions with Task-3 channels.