Yo Otsu

This study evaluates the effects of oxycodone prescribing and deprescribing in a mouse model of osteoarthritis, showing that polypharmacy worsens outcomes and sex differences exist in treatment response.

This study attempts to replicate findings that glutamate, AP5, or NMDA modulate glycine receptors but fails to reproduce the results, suggesting glycinergic tone is independent of excitatory activity.

This study investigates chloride regulation by cation-chloride cotransporters in mouse hippocampal parvalbumin interneurons and pyramidal cells, showing similar mechanisms and the critical role of KCC2 in maintaining inhibitory GABA signaling.