Ellen K. Gagliani

This study investigates how Gsx2 binds DNA cooperatively, revealing structural and thermodynamic mechanisms underlying its dimeric DNA binding and specificity.

This study uses a Drosophila Su(H) model to show that AOS-linked RBPJ variants cause developmental defects by sequestering Notch cofactors, leading to dysregulated target gene expression.

The paper shows that enhancers with SPS sites are more resistant to repression by Hairless co-repressor compared to those with CSL sites.