Author

Lisa M. Gutzwiller

Cincinnati Children's Hospital Medical CenterORCID 0000-0001-8583-8328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Brian A. GebeleiniD· 2 shared Ellen K. GaglianiiD· 2 shared Rhett A. KovalliD· 2 shared Yi KuangiD· 2 shared Aleksandra Turkiewicz· 1 shared Anna PyoiD· 1 shared Brittany CainiD· 1 shared David SprinzakiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Brian A. GebeleinORCID

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2 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedAug 11, 2022

A Drosophila Su(H) Model of Adams-Oliver Syndrome Reveals Notch Cofactor Titration as a Mechanism Underlying Developmental Defects

Ellen K. Gagliani, Lisa M. Gutzwiller, Yi Kuang…·Rhett A. Kovall

This study uses a Drosophila Su(H) model to show that AOS-linked RBPJ variants cause developmental defects by sequestering Notch cofactors, leading to dysregulated target gene expression.

11 citations

Drosophilastatistical model

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Developmental BiologyPLoS GeneticsPeer-reviewedSep 24, 2021

Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor

Yi Kuang, Anna Pyo, Natanel Eafergan…·Brian A. Gebelein

The paper shows that enhancers with SPS sites are more resistant to repression by Hairless co-repressor compared to those with CSL sites.

14 citations

Drosophilaexperimental assay

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