Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor
Yi Kuang, Anna Pyo, Natanel Eafergan, Brittany Cain, Lisa M. Gutzwiller, Ofri Axelrod, Ellen K. Gagliani, Matthew T. Weirauch, Raphael Kopan, Rhett A. Kovall, David Sprinzak, Brian A. Gebelein
The paper shows that enhancers with SPS sites are more resistant to repression by Hairless co-repressor compared to those with CSL sites.
PLoS Genetics · Sep 24, 2021Peer-reviewedDevelopmental Biology