Author

Soon Chul Kwon

Seoul National UniversityORCID 0000-0001-7271-6284Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:virus· 1

Frequent Co-Authors

Chang Hoon JiiD· 2 shared Da-Ha Park· 2 shared Eun Hye ChoiD· 2 shared Gee Eun LeeiD· 2 shared Jihoon LeeiD· 2 shared Su KimiD· 2 shared Yong Tae KwoniD· 2 shared Young Ho SuhiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Chang Hoon JiORCID

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2 papers

Recent·Most cited

Chemical N-degrons activate p62-mediated mitophagy to alleviate mitochondrial neuropathies

Soon Chul Kwon, Byeong-Seong Kim, Hyeyoon Kim, Dae Eun Kang, Gee Eun Lee, Eui Jung Jung, Min Ju Lee, Yeon Sung Son, Da-Ha Park, Daniel Youngjae Park, Jihoon Lee, Eun Hye Cho, Su Kim, Ah Jung Heo, Young Ho Suh, , Yong Tae Kwon

This study identifies ATB1071, a compound that activates p62-mediated mitophagy through Arg/N-degrons, showing therapeutic benefits in mitochondrial neuropathies and ischemia-reperfusion injury.

bioRxiv · May 8, 2026 · PreprintCell Biology

Targeted degradation of pathologic tau aggregates via AUTOTAC ameliorates tauopathy

Jihoon Lee, Su Kim, Hye Yeon Kim, Gee Eun Lee, Dong Won Lee, Eun Hye Jung, Ji Su Lee, Eun Hye Cho, Hong‐Beom Park, Da-ha Park, Soon Chul Kwon, Jeong Eun Noh, Hyo Sun Cha, Hans Jin-young Oh, Seung Hoon Lee, , Yong Tae Kwon

This paper demonstrates that AUTOTAC, a targeted degradation approach, reduces tau aggregates and improves symptoms in tauopathy models and companion dogs.

bioRxiv · Sep 10, 2025 · PreprintNeuroscience