Author

Daniel Youngjae Park

Seoul National University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Eun Hye ChoiD· 3 shared Yong Tae KwoniD· 3 shared Chang Hoon JiiD· 2 shared Da-Ha Park· 2 shared Gee Eun LeeiD· 2 shared Hee Yeon Kim· 2 shared Sung Hyun KimiD· 2 shared Yeon Sung SoniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCell Biology

Eun Hye ChoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chemical N-degrons activate p62-mediated mitophagy to alleviate mitochondrial neuropathies

Soon Chul Kwon, Byeong-Seong Kim, Hyeyoon Kim, Dae Eun Kang, Gee Eun Lee, Eui Jung Jung, Min Ju Lee, Yeon Sung Son, Da-Ha Park, Daniel Youngjae Park, Jihoon Lee, Eun Hye Cho, Su Kim, Ah Jung Heo, Young Ho Suh, , Yong Tae Kwon

This study identifies ATB1071, a compound that activates p62-mediated mitophagy through Arg/N-degrons, showing therapeutic benefits in mitochondrial neuropathies and ischemia-reperfusion injury.

bioRxiv · May 8, 2026 · PreprintCell Biology

AUTOTAC-mediated targeted degradation of transthyretin aggregates ameliorates hereditary transthyretin amyloidosis

Hee Yeon Kim, Daniel Youngjae Park, Eun Hye Cho, Yeon Sung Son, Sung Hyun Kim, Ki Woon Sung, Helena Sofia Martins, Maria João Saraiva, Maria Rosário Almeida, Chang Hoon Ji, Yong Tae Kwon

This study identifies the N-degron pathway's role in lysosomal degradation of TTRV30M aggregates and demonstrates the therapeutic potential of AUTOTAC-based degraders for hATTR.

bioRxiv · Feb 24, 2026 · PreprintCell Biology

Targeted degradation of pathogenic TDP-43 proteins in amyotrophic lateral sclerosis using the AUTOTAC platform

Daniel Youngjae Park, Hee Yeon Kim, Eun Hye Cho, Haneul Choi, Da-ha Park, Gee Eun Lee, Sung Hyun Kim, Hye Yeon Kim, Young Ho Suh, Jin-A Lee, Yong Tae Kwon

This paper develops AUTOTAC degraders to target and degrade pathogenic TDP-43 aggregates in ALS, showing efficacy in mice and entering clinical trials.

bioRxiv · Aug 31, 2025 · PreprintNeuroscience