Author

Nicholas F. Trojanowski

Brandeis UniversityORCID 0000-0001-7317-2266Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Andrew R FieldiD· 1 shared Charlie Harper· 1 shared Gina G. TurrigianoiD· 1 shared Jaclyn Essig· 1 shared Jordane DimidschsteiniD· 1 shared Joshua Reiser· 1 shared Juliet BottorffiD· 1 shared Kathryn C. AllawayiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Andrew R FieldORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 14, 2026

PV interneuron-targeted CRISPRa rescue of SCN1A haploinsufficiency in Dravet syndrome

Perry W.E. Spratt, Nicholas F. Trojanowski, Rajani M. George…·Kathryn C. Allaway

This study uses CRISPR activation to upregulate SCN1A in PV interneurons, improving survival and reducing seizures in Dravet syndrome models.

DOI 10.64898/2026.07.12.737793

𝕏 PostBluesky

NeuroscienceNeuronPeer-reviewedDec 16, 2020

Activity labeling in vivo using CaMPARI2 reveals electrophysiological differences between neurons with high and low firing rate set points

Nicholas F. Trojanowski, Juliet Bottorff, Gina G. Turrigiano

The paper uses CaMPARI2 to label neurons based on firing rates and finds that high activity neurons in mouse V1 have increased intrinsic excitability and lower spike adaptation, contributing to higher firing rate set points.

38 citations

mouseelectronic health records

𝕏 PostBluesky